Tinazzi, M., Del Vesco, C., Fincati, E., Ottaviani, S., Smania, N., Moretto, G., Fiaschi, A., Martino, D., Defazio, G. (2006) Pain and motor complications in Parkinson's disease. Journal of Neurology Neurosurg Psychiatry, Volume 77, pages 822-825

University of California, Berkeley

A significant association of pain with motor complications, but no correlation between dystonic and non dystonic pain. Pain may be a representative feature of Parkinson’s disease frequently associated with motor complications. The association is independent of a number of potentially relevant demographic and clinical variables.

Pain Perception in Parkinson's Disease

Pain and motor complications in Parkinson's disease

285 different pains were reported by the 123 patients. The results indicated that level of pain and number of symptoms are unrelated to age, stage, disease duration, or MMSE. No significant difference between the severity of nociceptive pain. The experienced pains were mostly from limbs.

Case study of Parkinson's patients

Chronic Subthalamic nucleus (STN) Deep Brain Stimulation (DBS) was applied on 40 patients with Parkinson's disease with mean age of 59. The pain was reduced by 84.2% a year after chronic STN (Preoperative = 1.7; Postoperative = 0.3). The outcome is sufficient for reducing the pain of the patients. However, the the multiple sources of pain are still not completely understood. Thus, it requires further investigation and attempts to operate this method on all Parkinson's disease patients.

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