Inhalation of spores can lead to asthma-like allergic reactions. Fungal balls, or aspergilloma, can form when hyphal colonies collect in the lungs. The fungal hyphae can invade the host tissues, leading to pulmonary hemorrhage and a bloody cough. In severe cases, the disease may progress to a disseminated form that is often fatal.

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aspergillosis is caused by the inhalation of *Aspergillus* spores

Aspergillosis

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Aspergillosis symptoms commonly include shortness of breath, wheezing, coughing, runny nose, and headaches. Fungal balls, or aspergilloma, can form when hyphal colonies collect in the lungs. This can lead to pulmonary hemorrhage and a bloody cough. In severe cases, the disease may progress and lead to death.

Signs and Symptoms of Aspergillosis

Diagnosing aspergillosis typically requires chest radiographs and a microscopic examination of tissue and respiratory fluid samples. Serological tests are available to identify *Aspergillus* antigens. In addition, a skin test can be performed to determine if the patient has been exposed to the fungus.

Diagnosis of Aspergillosis

Aspergillosis is treated with intravenous antifungal agents, including itraconazole and voriconazole. Allergic symptoms can be managed with corticosteroids because these drugs suppress the immune system and reduce inflammation. In disseminated infections, corticosteroids must be discontinued to allow a protective immune response to occur.

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