Second-generation antidepressants have been found to serve as a treatment for binge eating disorder. However, meta-analyses of their long-term effectiveness has found that while they cause significant reductions in binge-eating episodes and BMI in the short-term, these results tend to return to non-significance within 12 months after treatment. As such, while pharmacotherapy certainly has value in the management of binge eating disorder, it is unlikely to have lasting effects unless combined with other treatment methods.