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Racial Disproportionality in Covid Clinical Trials

  • Covid-19 clinical trials underrepresented racial minority groups as data from remdesivir trials have shown limited support for the safety and efficacy of the drug on racial minorities.
  • In the Adaptive Covid-19 Treatment Trial (ACTT-1) and Gilead-funded study, Black Americans accounted for only about 20% of the 1063 and 11% of the 396 patients respectively, despite the disproportionately high number of Covid-19 related mortalities where these trials were conducted.
  • Demographics of the clinical trials failed to reflect the demographics of Covid-19 morbidities and mortalities.
  • This research concluded that the lack of diversity in these trials may suggest that results are not generalizable to minority populations due to the disparities in health outcomes.

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Updated 2020-10-05

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SARS-CoV-2 (COVID-19)

Biomedical Sciences