Beauchamp, M., Dagher, A., Aston, J., & Doyon, J. (2003). Dynamic functional changes associated with cognitive skill learning of an adapted version of the Tower of London task. NeuroImage, 20(3), 1649-1660. doi:10.1016/j.neuroimage.2003.07.003

Dynamic functional changes associated with cognitive skill learning of an adapted version of the Tower of London task

PET:
-Dynamic functional changes associated with cognitive skill learning of an adapted version of the Tower of London task

University of California, Davis

- Magnetic resonance imaging (MRI)
- Functional magnetic resonance imagine (fMRI)
- Transcranial magnetic simulation (TMS) 
- Positron emission tomography (PET)
- Computerized tomography (CT)
- Electroencephalography (EEG)

Techniques for Brain Imaging

Magnetic Resonance Imaging (MRI) is a technique that creates images of brain structures. During an MRI, the individual is placed in a machine that produces a powerful magnetic field, causing the hydrogen atoms within the body's cells to align. When this field is switched off, the atoms return to their original state, emitting electromagnetic signals in the process. A computer analyzes these signals, which differ based on tissue density, to construct a detailed image of the brain. This method is commonly used to identify abnormalities such as tumors and injuries.

Magnetic Resonance Imaging (MRI)

Functional Magnetic Resonance Imaging (fMRI) operates on the same principles as MRI but focuses on revealing changes in brain activity over time. It achieves this by tracking variations in blood flow and oxygen levels, as increased neural activity in a brain region requires more oxygenated blood. This allows researchers to map which parts of the brain are active during specific cognitive processes.

Functional Magnetic Resonance Imaging (fMRI)

Positron Emission Tomography (PET) is a technique used to create images of an active, living brain. The procedure involves administering a mildly radioactive substance, known as a tracer, to an individual either orally or via injection. This tracer enters the bloodstream, and its concentration in different brain regions is monitored. Since increased brain activity correlates with higher blood flow, a computer can track the tracer's movement to generate a map that distinguishes between active and inactive brain areas during a specific task.

Positron Emission Tomography (PET)

A Computerized Tomography (CT) scan generates a comprehensive image of a specific section of the body, such as the brain, by combining multiple x-ray measurements. The underlying principle is that x-rays are absorbed at different rates by tissues of varying densities. A computer processes these differences to construct a detailed cross-sectional image, which is frequently used to detect abnormalities like tumors or significant brain atrophy.

Computerized Tomography (CT)

References for Studies Using Brain Imaging

Not necessarily an imaging technique, but it is used to uncover which parts of the brain are used in different tasks. It does this by disrupting the functioning of a particular area of the brain by creating a pulsating magnetic field using a stimulating coil over that portion of the brain.

Transcranial Magnetic Stimulation (TMS)

Electroencephalography (EEG) is a technique used to obtain a measure of the brain's overall electrical activity. It involves placing an array of electrodes on a person's scalp to record brainwaves. The resulting data provides high-precision information, accurate to the millisecond, about the frequency and amplitude of these waves, making it ideal for applications like sleep studies where precise spatial information is not required.

Electroencephalography (EEG)

The image presents a side-by-side comparison of three distinct brain imaging techniques. From left to right, they are: a Positron Emission Tomography (PET) scan, which uses a color map to visualize metabolic activity; a Computerized Tomography (CT) scan, which displays anatomical structures like bone and soft tissue in grayscale; and a Functional Magnetic Resonance Imaging (fMRI) scan, which overlays areas of brain activity, shown in orange, onto a detailed structural image.

Visual Comparison of PET, CT, and fMRI Scans

Functional Magnetic Resonance Imaging (fMRI) offers significant advantages over Positron Emission Tomography (PET) scans. Specifically, fMRI produces images with greater structural detail and provides better temporal accuracy, meaning it can pinpoint the timing of brain activity more precisely than PET scans.

Comparison of fMRI and PET Scans

Due to their high level of detail, both MRI and fMRI are valuable tools in psychological research. They are frequently used to compare the brains of healthy individuals with those of individuals diagnosed with psychological disorders. This comparative approach helps researchers identify specific structural and functional differences that may be associated with these conditions.

Using MRI and fMRI to Study Psychological Disorders

A cognitive neuroscientist is designing an experiment to determine the exact moment, down to the millisecond, that the brain's auditory cortex responds to a sudden, brief sound. Which of the following brain imaging techniques would be the most suitable for this specific research goal?

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