From performing the assay, neutralization titers significantly correlated with spike-binding titers. Although there was some variability, sera with 1:320 ELISA titers had a geometric mean 50% inhibitory dilution (ID50) of approximately 1:30. For the 1:960 titer, it was approximately 1:75, and for the 1:2880 titer it was approximately 1:550. When considering any activity above background (noise), approximately 50% of sera in the 1:80-1:160 titer range had neutralizing activity, 90% in the 1:320 range had neutralizing activity, and all sera in the 1:960 - 1:2880 range had neutralizing activity. These results can potentially validate use of antibody titers to refer for plasma donation and further investigation into neutralizing effects at varying titer levels.