Zanin, L., Saraceno, G., Panciani, P. P., Renisi, G., Signorini, L., Migliorati, K., & Fontanella, M. M. (2020). SARS-CoV-2 can induce brain and spine demyelinating lesions. Acta Neurochirurgica, 1-4.
https://link.springer.com/content/pdf/10.1007/s00701-020-04374-x.pdf

Smith College

Symptoms: 
- 54yr CoV-19 patient had anosmia and dysgeusia early, while seizures occurred as COVID-19 complication. 
- Two seizures starting from right frontotemporal region and diffusing in homologous contralateral hemisphere
- The delayed CNS damage appears mediated by the immune system 

Possible causes: 
- The pro-inflammatory state induced by the cytokine storm may be responsible of the activation of glial cells with subsequent demyelination 
- Alternative could be the production of antibodies against glial cells triggered by the virus, as a para-infective or post-infective phenomenon. 



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