Symptoms:

• 54yr CoV-19 patient had anosmia and dysgeusia early, while seizures occurred as COVID-19 complication.
• Two seizures starting from right frontotemporal region and diffusing in homologous contralateral hemisphere
• The delayed CNS damage appears mediated by the immune system

Possible causes:

• The pro-inflammatory state induced by the cytokine storm may be responsible of the activation of glial cells with subsequent demyelination
• Alternative could be the production of antibodies against glial cells triggered by the virus, as a para-infective or post-infective phenomenon.