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Relation
SARS-CoV-2 induces cytokine storm
- SARS-Cov-2 infection produce reactive oxygen species (ROS)
- ROS induce HIF1a (hypoxia induced Factor-1a)
- HIF1a induce transcription of proinflammatory cytokines
- Increased PD-1, IL-1, IL-6, TNFa
- Decreases anti-inflammatory cytokines
- Decreased IFNg
- Increases epithelial cell death
- Decreased T cell proliferation
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Updated 2021-05-15
Tags
COVID-19 and diabetes: Knowledge in progress
SARS-CoV-2 (COVID-19)
Biomedical Sciences