For participants taking hydroxychloroquine as postexposure prophylaxis, 40.1% reported side effects by day 5, compared to 16.8% in the placebo group. Nausea, loose stools, and abdominal discomfort were the most common side effects.

Santa Clara University

Google

13% of participants were either PCR confirmed or had compatible COVID-19 symptoms that developed during the 14 days follow up. There was not a significant difference between those that received hydroxychloroquine and those that received a placebo. 
P-value of 0.35 and an absolute difference of -2.4 percentage points. 

Patient outcomes of hydroxychloroquine as postexposure prophylaxis

No meaningful difference in effectiveness according to the time of starting the postexpsorue prophylaxis


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