The smooth endoplasmic reticulum is responsible for producing lipids, carbohydrates and detoxification of the cell. The smooth endoplasmic reticulum does not contain ribosomes embedded in the membrane which gives it a smoother appearance. 

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The endoplasmic reticulum is responsible for synthesizing molecules in the cell. It is make of a lipid bilayer and is connected by tubules and flat sacs called cisternae. 

There are two types of endoplasmic reticulum with their own molecules they synthesize. 
- Rough endoplasmic reticulum
- Smooth endoplasmic reticulum

Endoplasmic Reticulum

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The rough endoplasmic reticulum is covered with ribosomes that are bound to the cytoplasmic side of the membrane. The ribosomes synthesize proteins that are inserted into the membrane of the rough endoplasmic reticulum. These proteins bud off into transport vesicles to be further processing or go to the membranes of a different organelle. They could also leave the cell.

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