The pathogen *Streptococcus pyogenes*, which causes strep throat and other infections, establishes colonization by binding to fibronectin in the extracellular matrix of epithelial cells lining the upper throat (oropharynx).

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The extracellular matrix of host cells serves as a common site where microbial pathogens attach themselves to initiate and establish an infection.

Pathogen Attachment to the Eukaryotic Extracellular Matrix

https://openstax.org/details/books/microbiology/

Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology’s art program enhances students’ understanding of concepts through clear and effective illustrations, diagrams, and photographs.

Microbiology is produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press. The book aligns with the curriculum guidelines of the American Society for Microbiology.

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