A review of several studies concluded that psychotropic medication should not be a first response. This approach should only be used after non-pharmacological treatments fail. This is because the evidence on safety, efficacy, and dosage is few and far between.


When should psychotropic medications be used in Adults with Co-Occurring ASD and ID

Situations must be assessed with a person centered approach that takes into account how a person responds to a specific psychotropic medication where the optimal dosage is not clear.


Cedarville University

There is a significant lack of evidence to support the usage and efficacy of psychotropic medications to treat individuals with co-occurring autism and intellectual disabilities.


Polypharmacy of Psychotropic Medications in Individuals with Co-Occuring ID and ASD

McCarthy, J. M., & Chaplin, E. (2022). Adults with Intellectual Disability and Autism Spectrum Disorder: What Is the Evidence around the Use of Polypharmacy. International journal of environmental research and public health, 19(23), 15974. https://doi.org/10.3390/ijerph192315974

Adults with Intellectual Disability and Autism Spectrum Disorder: What Is the Evidence around the Use of Polypharmacy

- Behavioral Issues
  - Self injurious behavior, aggression, and agitation
- Women
- Those living in supervised residential facilities
- Age
- Lower Functioning

Predictors of Psychotropic Medication Usage in individuals with Autism

The Role of Clinicians in Prescribing Psychotropic Medications for Adults with Co-Occuring ID and ASD

Antipsychotics were the most common
  - Specifically risperidone and aripiprazole 
    - Used for irritability, aggression, self injury, and severe tantrums

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