DNA replication in bacteria occurs rapidly at approximately 1000 nucleotides per second, which is approximately ten times the speed of eukaryotes. It also occurs at a single origin to begin replication.

DNA Replication in Prokaryotes

Initiation of DNA replication involves many proteins to interact with the DNA to make it accessible to be replicated. In prokaryotes, there is one DNA sequence where initiation can begin but in eukaryotes there are many.

Initiation of DNA Replication

Elongation of DNA replication involves adding nucleotides to the DNA towards the direction of the replication fork. This is done by DNA polymerase.

Elongation of DNA Replication

The end of DNA replication must involve sealing of the DNA at the replication fork to make double stranded replicated DNA.

Termination of DNA Replication

The steps of DNA replication are shared between eukaryotes and prokaryotes. The steps of DNA replication are: 
1. Initiation
2. Elongation
3. Termination

University of Wisconsin - Madison

DNA replication is the copying of the genome. It happens in prokaryotic, archaeal, eukaryotic and viral genomes. DNA replication is semiconservative. This describes how, during DNA replication, the DNA is separated and single strands serve as the template for the synthesized DNA. This was determined by Matthew Meselson and Franklin Stahl in 1958. 

DNA Replication

https://openstax.org/details/books/microbiology/

Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology’s art program enhances students’ understanding of concepts through clear and effective illustrations, diagrams, and photographs.

Microbiology is produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press. The book aligns with the curriculum guidelines of the American Society for Microbiology.

OpenStax Microbiology Textbook

The Steps of DNA Replication

While eukaryotes and prokaryotes have some differences between their processes of DNA replication, they share many of the same proteins needed for replication. These are: 

- DNA Polymerase
- Helicase
- Topoisomerase
- Sliding Clamp
- Primase
- Single-stranded binding protein
- Ligase

Enzymes Involved in DNA Replication

- Lagging Strand
- Leading Strand
- Okazaki Fragment
- Replication Fork
- Replication Bubble

Key Components of DNA Replication

DNA Replication shares many of the same enzymes and components across organisms. However, there are key difference between many of them.

Here we designate the different types of DNA replication: 
- Prokaryotic DNA Replication
- Eukaryotic DNA Replication

Learn Before

Related

Learn After