Psychoplastogens have a range of therapeutic potential in treating neuropsychiatric diseases including anxiety disorder, mood disorders, PTSD, and addiction. The 5-HT receptor group also has an important role in the gut-brain axis and is linked to the pathophysiology of IBS via dysregulated serotonin signaling.

Michigan State University

Psychoplastogens class of compounds that take effect on neural plasticity in key circuits involved in brain health. Psychoplastogens include psychadelics, and produce a quantifiable change in plasticity within a short time frame (>72 h) post administration.

Psychoplastogens 

Meade, Elaine, et al. "Mycotherapy: Potential of Fungal Bioactives for the Treatment of Mental Health Disorders and Morbidities of Chronic Pain." Fungi and Fungal Metabolites for the Improvement of Human and Animal Life, Nutrition and Health, vol. II, 11 Mar. 2022, doi:https://doi.org/10.3390/jof8030290.

Mycotherapy: Potential of Fungal Bioactives for the Treatment of Mental Health Disorders and Morbidities of Chronic Pain

Psychedelics (or hallucinogens) are a class of psychoactive substances (Psychoplastogens) that produce changes in perception, mood, and cognitive processes, such as altering thinking, sense of time, and emotions. They can also cause a person to see or hear things that do not exist or are distorted. They can be naturally occurring or synthetic. Examples include:
- Lysergic acid diethylamide (LSD)
- Dimethyltryptamine (DMT)
- 3-[2-(Dimethylamino)ethyl]-1H-indol-4-yl dihydrogen phosphate (Psilocybin)
- Mescaline
- Peyote


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