A point mutation is when a single DNA base pair is changed to a different base pair.

Point Mutation

Missense mutations in the DNA cause a different amino acid to be translated after translation. The change in the amino acid may or may not affect the protein function depending on the location and chemical change in the amino acid residue in the protein. 

Missense Mutations

Conditional mutations are missense mutations where the phenotype is only visible in different environmental conditions.

Conditional Mutation

Nonsense mutations are a change in the DNA from an amino acid codon to a stop codon. This causes a protein to be shorter than the native form and it may not be functional anymore. 

Nonsense Mutations

Frameshift mutations are insertions or deletions of nucleotides into the DNA that affect the reading frame of the codons. This shifts the codons that the ribosome reads so it may code for a different protein or a premature stop codon. These mutations usually code for nonfunctional proteins.

Frameshift Mutations

Silent mutations in the DNA have no effect on the protein's structure because the mutation codes for the same amino acid prior to the mutation. This is due to redundancy in the genetic code. 

Silent Mutations

- Point Mutations
- Silent Mutations
- Missense Mutations
- Conditional Mutations
- Nonsense Mutations
- Frameshift Mutations

University of Wisconsin - Madison

Mutations in the genetic code occur at the DNA base pair level when a DNA base pair is changed. It may or may not have a noticeable change to the protein that is made due to redundancy in the genetic code. However, a mutation in the DNA can lead to a noticeable phenotype. 

Mutations

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Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology’s art program enhances students’ understanding of concepts through clear and effective illustrations, diagrams, and photographs.

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