1Cademy - Analysis of type I IFN response and T cell activation in severe COVID-19/HIV-1 coinfection

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Analysis of type I IFN response and T cell activation in severe COVID-19/HIV-1 coinfection - United States

This paper details a case study of an Ethiopian woman in the USA with a COVID-19 and HIV comorbidity who was tested for IFN-I response and T cell activation brought upon by the coinfection
Patient was given nose swab test which they tested positive to COVID-19 with and was admitted to the hospital with fever and elevated pulse
Patients additionally tested negative for a viral blood pneumonia test upon entry and all blood immune levels appeared normal
There was COVID-19 like lung spotting present as well as characteristic pneumonia spotted from lung scans
Patient was hospitalized for 14 days and kept on oxygen, upon day 14 they tested negative via 2 nasal swabs 24 hours apart
Additionally, over hospital stay IFN expression and T cell activation remained at normal levels

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Updated 2020-09-08

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