Archaeal walls are different from bacteria because they do not contain peptidoglycan. Some contain pseudopeptidoglycan or have a cell wall made of glycoproteins or sugars. Some lack a cell wall entirely. 

University of Wisconsin - Madison

Peptidoglycan makes up the cell walls of bacteria. It is composed of alterating long chain molecules called N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM). NAM and NAG are connected to each other with peptide bridges. Peptidoglycan is only in bacteria which makes it a key target for antibiotics.

Peptidoglycan

Archaea are single-cellular organisms that do not contain nuclei. Archaea different from bacteria because archaeal membranes and cell walls are structurally different.

Archaea

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Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology’s art program enhances students’ understanding of concepts through clear and effective illustrations, diagrams, and photographs.

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Types of Bacterial Cell Walls

Archaeal Cell Walls vs. Bacterial Cell Walls

- Crenarchaeota
- Euryarchaeota
- Korarchaeota
- Nanoarchaeota
- Thaumarchaeota

Major Phylum of Archaea

Archaeal membranes differ from bacterial membranes because the phospholipids in archaeal membranes are linked with ether linkages and not ester linkages. While bacterial cell membranes are often bilayers, many archaeal membranes are monolayers. 

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