Concept

Background Information for Longitudinal Evaluation and Decline of Antibody Responses in SARS-CoV-2 Infection

SARS-CoV-2 is a betacoronavirus responsible for COVID-19. The Spike (S) proteins on the viral envelope of the coronavirus are what allow the virus to bind to the angiotensin enzyme-2 (ACE-2) receptor binding site on host target cells via the receptor binding domain. Many antibodies are produced within 1-2 weeks post onset of symptoms (POS) including IgM, IgA, and IgG, but the main focus of this study was on neutralizing antibodies (nAbs). It was found that antibody responses to SARS-CoV-2 can be seen 12-34 months after infection.

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Updated 2020-07-23

Tags

SARS-CoV-2 (COVID-19)

Biomedical Sciences