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BioRxiv Papers Related to COVID-19 Human Physiology

  • The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells.
  • Genetic variants in TMPRSS2 and Structure of SARS-CoV-2 spike glycoprotein and TMPRSS2 complex
  • SARS-CoV-2 infection in the lungs of human ACE2 transgenic mice causes severe inflammation, immune cell infiltration, and compromised respiratory function
  • SARS-CoV-2 Spike protein hijacks VEGF-A/Neuropilin-1 receptor signaling to induce analgesia
  • ACE2-independent interaction of SARS-CoV-2 spike protein to human epithelial cells can be inhibited by unfractionated heparin
  • FDA approved calcium channel blockers inhibit SARS CoV 2 infectivity in epithelial lung cells
  • Extracellular superoxide dismutase, a molecular transducer of health benefits of exercise
  • SARS-CoV-2 infects brain choroid plexus and disrupts the blood-CSF-barrier

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Updated 2020-08-22

Contributors are:

Dominica Cao
Dominica Cao
🏆 3
Ben Kessler
Ben Kessler
✔️ 2
Alan Reardon
Alan Reardon
✔️ 1
Natalia Glowacka
Natalia Glowacka
✔️ 1
sojin lee
sojin lee
✔️ 1

Who are from:

Smith College
Smith College
🏆 3
Michigan State University
Michigan State University
✔️ 2
Johns Hopkins University
Johns Hopkins University
✔️ 1
Northwestern University
Northwestern University
✔️ 1
University of Michigan - Ann Arbor
University of Michigan - Ann Arbor
✔️ 1

Tags

SARS-CoV-2 (COVID-19)

Biomedical Sciences

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