When the mood disturbance is asserted to be attributable to the physiological effect of a specific, usually chronic medical condition, the diagnosis of bipolar and related disorders is made 


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Differential diagnoses to Cyclothymic Disorder include:

- Bipolar and Related Disorder Due to Another Medical Condition

- Substance/Medication-Induced Bipolar and Related Disorder and Substance/Medication-Induced Depressive Disorder

- Bipolar I Disorder, With Rapid Cycling and Bipolar II Disorder, With Rapid Cycling

- Borderline Personality Disorder


Differential Diagnoses to Cyclothymic Disorder

American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed., Text revision). https://doi.org/10.1176/appi.books.9780890425596

DSM-5-TR

Bipolar and Related Disorder Due to Another Medical Condition as a Differential Diagnosis to Cyclothymic Disorder

The difference between those disorders——substance/medication-induced bipolar and related disorder and substance/medication-induced depressive disorder——and cyclothymic disorder is about whether substance/medication is etiologically related to the mood disturbance. 


Substance/Medication-Induced Bipolar and Related Disorder and Substance/Medication-Induced Depressive Disorder as Differential Diagnoses to Cyclothymic Disorder

Both disorders may resemble cyclothymic disorder by virtue of the frequent marked shifts in mood, but bipolar I disorder and bipolar II disorder with rapid cycling require the full mood episodes, and cyclothymic disorder not.


Bipolar I Disorder, With Rapid Cycling, and Bipolar II Disorder, With Rapid Cycling as Differential Diagnoses to Cyclothymic Disorder

Both borderline personality disorder and cyclothymic disorder have recurrent, brief marked shifts in mood with potentially self-damaging behaviors. 


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