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Can Alzheimer's Disease be inherited?
- ~1% of patients have early-onset AD due to inheriting autosomal dominant mutations in genes whose protein products are involved in the production of AB peptides.
- Genetic risk factor for more common form of AD is the APOE ε4 gene which encodes the apoE4 lipid carrier
- Greater than 60% of caucasian patients with AD carry at least one APOE ε4 gene
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Alzheimer's Disease Library
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Warning Signs of Alzheimer's Disease
Diagnosing Alzheimer's Disease
Can Alzheimer's Disease be inherited?
Ageing and Alzheimer's Disease
Treatments for Alzheimer's Disease
Alzheimer's Disease Neurofibrillary Degeneration Stages
The role of Tau proteins in Alzheimer's Disease
Potential Areas of Research
The Source of Alzheimer's vs Age-Related Memory-Loss
Reference for Types of Alzheimer's Disease
Types of Alzheimer's Disease
Solomon Carter Fuller
An 80-year-old individual has been experiencing increasing difficulty over the past few years. Initially, they would forget recent conversations. Now, they frequently get lost in their own neighborhood, struggle to manage their finances, and have trouble with basic tasks like dressing themselves. Their family notes this decline is steady and getting worse. Based on this pattern of progressive and severe cognitive decline that interferes with daily life, which statement best characterizes the underlying issue?