Comparison of Unfractionated and Low-Molecular-Weight Heparins in Anti-ACE2-Treated RT4 Cells
In RT4 cells pre-treated with anti-ACE2 antibodies, unfractionated heparin strongly inhibited SARS-CoV-2 S1S2 protein binding, whereas the low-molecular-weight heparins dalteparin and enoxaparin acted as partial inhibitors and were less potent than unfractionated heparin.
0
1
Contributors are:
Who are from:
Tags
SARS-CoV-2 (COVID-19)
Biomedical Sciences
Related
Findings supporting heparin use in COVID-19 patients for patients at high risk of coagulopathy from retrospective study in Wuhan, China
Prophylactic and Therapeutic Serum Concentrations of Unfractionated Heparin (UFH)
Prophylactic and Therapeutic Serum Concentrations of Low Molecular Weight Heparins (LMWH)
SARS-CoV-2 S Protein May Have Multiple Heparin Binding Sites
Comparison of Unfractionated and Low-Molecular-Weight Heparins in Anti-ACE2-Treated RT4 Cells
Comparison of Unfractionated and Low-Molecular-Weight Heparins in Anti-ACE2-Treated RT4 Cells