Drug-Induced Neurologic Conditions Library 

- Cerebrovascular Effect
- Cognitive Impairment and Delirium
- Neuroleptic Malignant Syndrome
- Movement Disorders
- Seizure Disorders
- Serotonin Syndrome
- Insomnia

Examples of Drug-Induced Neurologic Conditions

May result from single-agent drugs but are more likely to occur when multiple agents that have side effects/risk are administered together 

Rutgers University

New York University

Drug Effects 

Lane RJ, Routledge PA. Drug-induced neurological disorders. Drugs. 1983;26(2):124-147. doi:10.2165/00003495-198326020-00002



Drug-Induced Neurologic Conditions

A condition in which, with repeated exposure to a drug, an individual becomes less responsive to a constant dose. 
 
- Metabolic tolerance 
- Functional tolerance 
- Behavioral Tolerance
- Cross-tolerance 
- Withdrawal symptoms
- Sensitization 


Drug tolerance

The amount of drug that reaches the brain and the speed with which is starts acting are determined in part by the drug's route of administration. 
- bioavailable
- biotransformation
- pharmacokinetics
- blood brain barrier

Drugs are administered and eliminated in many different ways

Drug-Induced Neurologic Conditions 


Some major categories of psychoactive drugs impact and affect behavior: 
- antipsychotics relieve schizophrenia
- antidepressants reduce chronic mood problems
- anxiolytics combat anxiety
- opiates relieve pain

Neuroactive drugs used to ease the symptoms of injury or psychiatric illness

Some of the major classes of neuroactive drugs that modify consciousness include: 
- cannabinoids 
- stimulants
- hallucinogenics 

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