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Dysbiosis in Anorexia Nervosa
Dysbiosis, or microbial imbalances in the gut, is linked with anorexia nervosa. Despite some inconsistencies in the literature, anorexia nervosa patients have been found to have reduced gut microbial diversity compared to healthy controls, characteristic of dysbiosis and often found in other illnesses such as obesity and inflammatory bowel diseases. Low diversity in the gut ecosystem is associated with depression, anxiety, and other eating disorder psychopathology among anorexia nervosa patients, although this is likely dependent on greater severity since this relationship was not found among subthreshold healthy controls. Patients have also been found to display increased levels of Enterobacteriaceae species, such as E. Coli in stool samples as the gut environment favors pathogenic bacterial species to alter the diet of the host. Although it is unclear in dysbiosis causes or results from anorexia nervosa, there is nonetheless a clear connection between the disorder and the gut microbiome.
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