An enzyme without its necessary cofactor or coenzyme and, as such, is inactive

Apoenzyme

An enzyme with its necessary cofactor or coenzyme and, as such, is active

Holoenzyme

Enzymes can. be classified depending on whether they are interacting with their necessary cofactors of coenzymes. These include:

- Apoenzymes
- Holoenzymes

University of Notre Dame

A molecule that serves to promote conformational change and effective functioning of their associated enzymes

(Photo credits in References)

Enzyme Helper Molecule

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Helper molecules that bind to enzymes and help them function include:

- Cofactor
- Coenzyme

Types of Enzyme Helper Molecules

Enzyme Classifications Based on Helper Molecules

Enzyme Helper Molecule Diagram (Figure 8.7). Reprinted from OpenStax Microbiology (p. 300), by N. Parker, M. Shneegurt, A.-h. Thi Tu, B. M. Forester, and P. Lister, 2016, Rice University. Copyright 2016 by Rice University.

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