Wang, T., Liu, X., Guan, J., Ge, S., Wu, M., Lin, J., & Yang, L. (2019, March 05). Advancement of multi-target drug discoveries and promising applications in the field of Alzheimer's disease. Retrieved from https://www.sciencedirect.com/science/article/abs/pii/S0223523419302089


State University of New York at Stony Brook

- Alzheimer's disease is a progressive chronic disease. It's "a type of dementia that affects memory, thinking and behavior"; over time, these symptoms progressively interfere with daily tasks.
- It's the 6th leading cause of death. Current treatments can alleviate the symptoms but can't stop the progression of Alzheimer's.

Alzheimer's Disease

 Alzheimer's Association

Multi-target drug discovery

Multi-target drugs have displayed a higher efficacy, improved safety, and simpler administration as compared to a single target. Multi-target drugs are different in the way in that they have multiple biological targets and generally contain several main steps in target identification, validation, hits identification, and lead component optimization. 

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