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Nernst Equation
The Nernst equation predicts the membrane potential at which the processes of diffusion and the active transport of the sodium-potassium pump reach equilibrium. The Nernst equation can therefore help to predict the resting membrane potential. However, it is not very accurate because it does not take into account how the selective permeability of the cellular membrane to each ion affects the membrane potential, as with the Goldman equation. The Nernst Equation is given by the following: 58/(electrical charge ion x in millivolts (mV)) X log((concentration of x outside)/(concentration of x inside)).
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Nernst Equation
Measuring Membrane Potential
Microelectrode
Goldman Equation
Sodium-Potassium Pump
Pressures on Ions During Resting Potential
Imagine a neuron is exposed to a substance that specifically blocks the protein pump responsible for moving three sodium ions out of the cell for every two potassium ions it moves in. Assuming ion channels still allow for some passive leakage, what would be the most likely consequence for the neuron's resting membrane potential over time?
Imagine a neuron is exposed to a substance that specifically blocks the protein pump responsible for moving three sodium ions out of the cell for every two potassium ions it moves in. Assuming ion channels still allow for some passive leakage, what would be the most likely consequence for the neuron's resting membrane potential over time?