Using functional magnetic resonance imaging, (fMRI), research has shown neural differences between those with and without prolonged grief disorder. In those with prolonged grief disorder, there is a higher level of activation in the nucleus accumbens meaning a higher activation in the reward centers of the brain. This activation in the reward center is associated with the deceased which suggests a cause for impaired judgement following the loss. Additionally, prefrontal regions, whole brain volume and cognitive function can differ in those with prolonged grief disorder versus those without.