Untreated prolonged grief disorder can lead to a number of issues including substance abuse, suicidal thoughts, trouble sleeping, and compromised immune function. This compromised immune function can result in cancer and other severe health issues. Additionally, about 5-10% of adolescents will experience post-traumatic stress disorder and depression along with prolonged grief disorder following the loss. Prolonged grief disorder can play a significant role in triggering other psychiatric disorders. A sample was taken in which it was found that major depressive disorder had a prevalence of 55%, 48% with PTSD, and 62% with anxiety disorders (Szuhany). In summary, prolonged grief disorder can create a higher risk of mortality as a result of many of the aforementioned effects.