Relation

Newly-diagnosed diabetes and admission hyperglycemia predict COVID-19 severity by aggravating respiratory deterioration

  • The objective of this study was to evaluate the role of pre-existing diabetes, newly-diagnosed diabetes, and hyperglycemia in the severity of symptoms in COVID-19 patients.

  • The data for this study was obtained from an outbreak hospital in North-East Italy and 413 patients who were hospitalized between February and April 2020 were evaluated.

  • 107 of the 413 patients had diabetes and 21 of them were newly-diagnosed patients.

  • Diabetic patients were older, had more comorbidities, were admitted to the ICU more, and had a higher mortality rate than non-diabetic patients.

  • It was also observed that in patients with newly-diagnosed diabetes, a higher ICU admission rate and a higher mortality rate than patients with pre-existing diabetes was present.

  • Hyperglycemia was associated with COVID-19 severity and was apparent when observed admission glucose levels.

  • These hyperglycemic conditions were met with an adverse outcome due to worsened respiratory function.

  • Overall, newly-diagnosed diabetes and hyperglycemia at admission are important factors in the severity of COVID-19 symptoms and this is due to worsened respiratory function.

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Updated 2020-12-02

Tags

SARS-CoV-2 (COVID-19)

Biomedical Sciences