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Physiological Changes During the Fight-or-Flight Response

Activation of the fight-or-flight response, prompted by a surge of epinephrine and norepinephrine, initiates a cascade of physiological adjustments to prepare the body for a threat. These changes include:

  • Pupil dilation
  • Increased heart rate and blood pressure
  • Heavy breathing and dilation of bronchi
  • Perspiration
  • Muscle tension
  • Inhibition of digestion (causing sensations like 'butterflies in the stomach') and salivation
  • Stimulation of glucose breakdown and release from the liver
  • Relaxation of the bladder

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Updated 2026-05-02

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