Cytokine storm has been common in SARS-CoV-2 virus infection. It involves the overproduction and release of inflammatory cytokines resulting in the recruitment of a large amount of immune cells and causing an immune response so strong it can result in organ damage and failure. In COVID-19 it has been noted that there is potential injury to the liver as a result of this powerful immune response. Since even small changes in liver function affect the clearance and metabolism of substances in the body, it would not be strange to see this effect in COVID-19 patients. In fact, in previous research on viral infection the inflammatory response has caused a suppression of CYP enzymes, enzymes primarily in the liver that are responsible for the metabolism of numbers substances in and that enter the body. It would not completely wrong to assume that this will affect medication taken by those positive for COVID-19 whether that medication is for treating the disease or for other conditions they previously had. This will affect the dosing and whether or not certain drugs should even continue to be used in the patient. Furthermore, those with comorbidities like diabetes and hypertension are much more likely to contract COVID-19 and the medications they are on to treat these conditions could be affected.