*Candida albicans* has many virulence factors like adhering to cells and forming biofilms. They can also create hydrolases such as proteases, which allow them to spread more quickly. 

Virulence Factors of *Candida albicans*

What is the primary function of proteases?

Which of the following best describes the action of proteases?

Which of the following processes is directly facilitated by proteases?

Which of the following is a result of protease activity?

A protease is an enzyme that breaks down proteins into smaller peptides or amino acids by hydrolyzing the peptide bonds between amino acids.

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Enzymes break down proteins such to release peptides for cellular uptake. Cells then are able to further breakdown amino acids into molecules that can be used in pyruvate oxidation and the citric acid cycle.

Protein catabolism

Some general classes of exoenzymes include:
- Glycohydrolases
- Nucleases
- Phospholipases
- Proteases

Types of Exoenzymes

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Proteases

Glycohydrolase is an enzyme that breaks down complex sugars into simpler sugars by hydrolyzing glycosidic bonds. An example is Hyaluronidase S found in *Staphylococcus aureus* Hyaluronidase degrades hyaluronic acid that cements cells together to promote spread.

Glycohydrolases

A phospholipase is an enzyme that breaks down phospholipids by breaking the bonds in their molecular structure. This process can release fatty acids, glycerol, and other products from the phospholipids which then degrades phospholipid bilayer of host cells, causing cellular lysis,

Phospholipases

A nuclease is an enzyme that hydrolyzes the bonds between nucleotides in nucleic acids like DNA and RNA.

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