Concept

Psychoneuroimmunology (PNI)

Psychoneuroimmunology is the scientific field dedicated to studying the interactions between psychological factors, such as stress, and the body's immune system. The term was introduced in 1981 in a book that reviewed evidence of associations between the brain, the endocrine system, and the immune system. The field's development was largely spurred by the discovery of a fundamental connection between the central nervous system and the immune system.

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Updated 2025-10-09

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