Intereferon Beta production is inhibited resulting in cell death. The Aedes and Culex species of mosquitoes are the vectors that transmit the arbovirus to susceptible populations. 

Tulane University

Georgetown University

- Pathogenesis/Vector
- Presentation of Maternal Infection
- Diagnosis
- Fetal/Neonatal Abnormalities
- Vaccines

Rift Valley Fever

A viral disease most often spread to humans from domesticated animals in sub-Saharan Africa. Rift Valley Fever is more likely to cause severe illness in the animals than in the humans the virus is spread to.

Nausheen, F., S. Bashir, S., &amp; N. Atapattu, D. (2018). Pregnancy associated arbovirus infections. Clinical Microbiology and Infectious Diseases, 3(2). https://doi.org/10.15761/cmid.1000138 

Pregnancy Associated Arbovirus Infections

IgM-ELISA, antigen detection ELISA and PCR diagnostic tests are used to detect Rift Valley Fever

Diagnosing Rift Valley Fever

Rift Valley Fever Pathogenesis/Vector

Clinical manifestations of Rift Valley Fever in pregnant women include fever, joint pain, rash, hepatic dysfunction, meningitis and hemorrhage. 

Maternal Rift Valley Fever Infection Presentation

Abortions, rash, hepato-splenomegaly with ALT/AST elevation and bleeding diathesis

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