Refers to a drug's ability to cause a particular action in a given cell population.

Calvin College

The following are evaluated properties when optimizing a lead in drug design:

- Binding mechanisms
- Pharmacodynamic (interaction with lead target)
- Pharmacokinetic (ability to reach and bind to target)
- Potency 
- Safety
- Selectivity (particular population vs. another)
- Specificity (action in population)
- Stability
- Toxicological


Drug Design Properties

Mencher, S. K., & Wang, L. G. (2005). Promiscuous drugs compared to selective drugs (promiscuity can be a virtue). BMC clinical pharmacology, 5, 3. https://doi.org/10.1186/1472-6904-5-3

Promiscuous drugs compared to selective drugs (promiscuity can be a virtue)

Refers to a drug's ability to prefer affecting a particular cell population over others.  

Selectivity in Pharmacology

Specificity in Pharmacology

The study of how pharmaceutical drugs affect living systems, especially the  biochemical and physiological consequences that result from taking such drugs. 



Pharmacodynamics 

The study of how living systems affect drugs. Pharmacokinetics studies the uptake of drugs by the body, the biotransformation they undergo, the distribution of drugs and their metabolitites in the tissues, and their subsequent elimination from the body.

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