Studies Opposing Hydroxychloroquine as a COVID-19 Intervention
A body of clinical research, including randomized controlled trials and multinational observational studies, has demonstrated that hydroxychloroquine (HCQ) is not an effective intervention for COVID-19. Across different stages of the disease—from post-exposure prophylaxis and early mild cases to hospitalized patients—these studies generally found no significant reduction in mortality or symptom severity, and some identified increased risks of adverse cardiovascular effects.
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SARS-CoV-2 (COVID-19)
Biomedical Sciences
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A pilot study of hydroxychloroquine in treatment of patients with moderate COVID-19
Hydroxychloroquine as Prophylactic Treatment for COVID-19
Effect of Hydroxychloroquine in Hospitalized Patients with COVID-19: Preliminary results from a multi-centre, randomized, controlled trial
Observational Study of Hydroxychloroquine in Hospitalized Patients with COVID-19
Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State
Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis
Hydroxychloroquine for Early Treatment of Adults with Mild Covid-19: A Randomized-Controlled Trial