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Superantigens
Superantigens are exotoxins that trigger a nonspecific stimulation of immune cells to secrete cytokines. The overproduction of cytokines, known as a cytokine storm, triggers a strong immune and inflammatory response that can lead to life-threatening conditions such as high fevers, low blood pressure, multi-organ failure, shock, and death.
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Biomedical Sciences
Ch.3 The Cell - Microbiology @ OpenStax
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Microbiology @ OpenStax
Ch.1 An Invisible World - Microbiology @ OpenStax
Ch.15 Microbial Mechanisms of Pathogenicity - Microbiology @ OpenStax
Related
Intracellular Targeting Exotoxins
Membrane Disrupting Exotoxins
Which of the following correctly describes the three classes of exotoxins?
Which class of exotoxins is primarily involved in disrupting the cell membrane?
Which class of exotoxins can cause an excessive immune response by activating a large number of T-cells?
Which class of exotoxins targets the inside of host cells to interfere with cellular functions?
Superantigens
Epitopes
Superantigens
Learn After
What is the primary effect of superantigens on the immune system?
Which of the following conditions can result from the cytokine storm triggered by superantigens?
How do superantigens differ from regular antigens in their interaction with the immune system?
What is a cytokine storm, and how is it related to superantigens?