Having a positive family history of bipolar disorder (BP) is a strong risk factor for developing the condition, especially among first-degree relatives. It can lead to earlier onset and more severe illness. Studies show that 5-19% of offspring of parents with BP develop BP themselves by young adulthood. These offspring also face a higher risk of other psychiatric conditions like depression and anxiety, making them an easily identifiable population at ultra-high risk for early-onset psychiatric disorders, particularly BP.