Data were generated by the O’Beirne research group. The relationship between ACE2 expression in the small airway epithelium (SAE) and average monthly pollution levels in New York City, using data from the EPA, was assessed. There was no difference reported between expression and pollution levels in nonsmokers (white dots), smokers (gray dots), or a combination of the two groups. It should be noted that the maximum 30-day mean PM2.5 concentration was 18 μg/m^3 which is considered safe by the EPA.