Anaplasmosis causes causes fever and flu-like symptoms.

Signs and Symptoms of Anaplasmosis

*Anaplasma* has five major virulence factors: three are adherence factors and two factors that allow the pathogen to avoid the human immune response.

Virulence Factors of *Anaplasma*

What is the cause of Anaplasmosis?

Which of the following vectors is primarily responsible for transmitting Anaplasmosis?

Which of the following symptoms is commonly associated with Anaplasmosis?

Which of the following diagnostic methods is commonly used to confirm Anaplasmosis?

Anaplasmosis is caused by the pathogen *Anaplasma phagocytophilum*.

University of Michigan - Ann Arbor

Diseases that require arthropod vectors:
- Anaplasmosis
- Ehrlichiosis
- Epidemic Typhus
- Murine (Endemic) Typhus
- Rocky Mountain Spotted Fever
- Lyme Disease
- Relapsing Fever
- Trench Fever

Zoonotic Febrile Diseases

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Anaplasmosis

Ehrlichiosis is caused by caused by the BSL-2, obligate intracellular pathogen *Ehrlichia chaffeensis*.

Ehrlichiosis

Epidemic Typhus is caused by the pathogen *Rickettsia prowazekii* and is transmitted by body lice, *Pediculus humanus*.

Epidemic Typhus

Murine (Endemic) Typhus is caused by  the pathogen *Rickettsia typhi*

Murine (Endemic) Typhus

Rocky Mountain Spotted Fever is caused by the pathogen *Rickettsia rickettsii* 

Rocky Mountain Spotted Fever

Lyme Disease is caused by the spirochete *Borrelia burgdorferi*

Lyme Disease

Relapsing fever can be caused by two pathogens: *B. recurrentis*, causing louseborne relapsing fever, and *B. hermsii*, causing tickborne relapsing fever.

Relapsing Fever

Trench Fever is caused by the pathogen *Bartonella quintana*.

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