Concept

Associated Features of Depressive Disorder Due to Another Medical Condition

When diagnosing Depressive Disorder Due to Another Medical Condition, establishing causality (etiology) between the medical condition and the depression is the most important variable. Medical conditions commonly associated with this depressive disorder include:

  • Autoimmune disorders (e.g., systemic lupus erythematosus) and vitamin deficiencies (e.g., vitamin B12)
  • Endocrine conditions (e.g., Cushing’s syndrome, hypothyroidism)
  • Focal lesions (e.g., cerebrovascular accident, traumatic brain injury, neoplasm)
  • Huntington’s disease
  • Multiple sclerosis
  • Parkinson’s disease.

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Updated 2026-06-28

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