- Evolved as a result of a need to develop and test the germ theory of disease as well as the need to search for ways to prolong the spoilage of agricultural products
- Initial advances in bacteriology focused on finding bacteria that caused a certain disease
- Koch's Postulates were often used to prove this relationship between the pathogen and the disease

History of the Study of Bacteriology

- Recent work in bacteriology has been focused on vaccines as well as antibiotics

Modern Focuses of Bacteriology

Bacteriology is the study of bacteria and how that affect human health as well as agriculture

Michigan State University

- Virology
- bacteriology
- protistology
- mycology
- immunology 
- parasitology

Disciplines in microbiology

Bacteria are single celled, prokaryotic organisms that are capable of living in extreme conditions and have cell walls composed of peptidoglycan. They are either heterotrophic or autotrophic and can be harmless or cause disease (Mycobacterium tuberculosis).

Bacteria

- Shiel Jr., W. C., Dr. (2018, December 11). Definition of Bacteriology. Retrieved February 22, 2021, from https://www.medicinenet.com/bacteriology/definition.htm
- Baron S, editor. Medical Microbiology. 4th edition. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Introduction to Bacteriology. Available from: https://www.ncbi.nlm.nih.gov/books/NBK8120/

References for Disciplines of Microbiology

The study of viruses and virus like agents. It deals heavily in their structure, classification, evolution, method of infection, effects of infection and how to cure or treat the infections.

Virology

Bacteriology

Protistology

Mycology

Parasitology

Immunology

Which of the following disciplines in microbiology focuses on the study of viruses?

Which discipline in microbiology is primarily concerned with the study of fungi?

Which discipline in microbiology focuses on the study of the immune system?

Which discipline in microbiology is primarily concerned with the study of parasites?

Diseases that require arthropod vectors:
- Anaplasmosis
- Ehrlichiosis
- Epidemic Typhus
- Murine (Endemic) Typhus
- Rocky Mountain Spotted Fever
- Lyme Disease
- Relapsing Fever
- Trench Fever

Zoonotic Febrile Diseases

TSS is caused by a toxemic infection of the pathogen *Staphylococcus aureus*.

Toxic Shock Syndrome (TSS)

Streptococcal Toxic Shock-like Syndrome is caused by the pathogen *Streptococcus pyogenes*. 

Streptococcal Toxic Shock-like Syndrome

Puerperal Sepsis is most often caused by the pathogen *Streptococcus pyogenes*, but can also be caused by *Streptococcus spp., Staphylococcus spp., Enterococcus spp., Chlamydia spp., Escherichia coli, Klebsiella spp., Proteus spp., Peptostreptococcus spp., Bacteroides spp.,* and *Clostridium spp.*

Puerperal Sepsis

Infectious Arthritis can be caused by many bacteria, most notably caused by the pathogens *S. aureus* or *Neisseria gonorrhoeae*. 

Infectious Arthritis

This inflammation of bone tissue is most commonly caused by the pathogen *S. aureus*, but can also be caused by *M. tuberculosis, Pseudomonas aeruginosa, Streptococcus pyogenes, S. agalactiae*, Enterobacteriaceae species, and other microorganisms

Osteomyelitis

Rheumatic Fever is caused by infections of *S. pyogenes* that have nonsuppurative sequelae.

Rheumatic Fever

Bacterial Endocarditis can be caused by an infection of any of the following pathogens: *Staphylococcus aureus, viridans streptococci, Enterococcus faecalis, Haemophilus spp., Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens*, and *Kingella kingae*.

Bacterial Endocarditis 

Bacterial Pericarditis can be caused by *Staphylcoccus spp.* or *Streptococcus spp.*

Bacterial Pericarditis 

Gas Gangrene is caused by the endospores of the pathogen *Clostridium perfringens*.

Gas Gangrene

Tularemia, also known as rabbit fever, is caused by the pathogen *Francisella tularensis*.

Tularemia

There are four pathogens that can cause Brucellosis in humans: *B. abortus, B. canis, B. suis*, and *B. melitensis*.

Brucellosis

Cat Scratch Disease is caused by the pathogen *Bartonella henselae.*

Cat Scratch Disease

Rat-bite fever can be caused by two pathogens: *Streptobacillus moniliformis* or *Spirillum minor*

Rat- Bite Fever

Plagues are a disease that affects humans and other mammals. It is caused by the bacterium, *Yersinia pestis*. Humans usually get the plague after being bitten by a rodent flea that is carrying the plague bacterium or by handling an animal infected with the plague.

Plague

- The Immune System
- CDC
- Morphology and Classification of Bacteria

References for Bacteria

These are diseases caused by bacteria and spread to humans by arthropods.

Vector borne bacterial diseases

Bacteria are classified based on size, shape and arrangement. 

Morphology & Classification of Bacteria

- Cell Wall
- Plasma Membrane
- Cytoplasm
- Ribosomes
- Mesosomes
- Cytoplasmic Inclusions
- Nucleoid
- Capsule
- Flagella
- Pilus
- Fimbriae
- Plasmid DNA
- Endospore
- Inclusion Bodies

Bacterial Structures

Bacteria are diverse in their functions, structure and genomes. Some important classes and phyla among bacteria are:
- Proteobacteria
- Nonproteobacteria Gram-Negative Bacteria 
- Phototrophic Bacteria
- Gram-Positive Bacteria
- Deeply Branching Bacteria

Bacterial Diversity

Bacterial vaccines are made from whole bacteria, their secreted toxins, or capsular polysaccharides.

- Live-attenuated bacterial vaccine

- Vaccines that generate toxin-specific neutralizing antibodies

- Subunit/Conjugate vaccines

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