Deep Brain Stimulation to the Nucleus Accumbens (NAcc DBS) for Anorexia Nervosa Treatment Outcomes
Clinical symptoms, social functioning, mental status, BMI, mood, and anxious and obsessive symptoms were assessed at 6 months and 24 months post-operation. At 6 months, there were significant improvements in BMI (15.29 ± 2.28 kg/m2) and psychiatric symptoms, with no effects on cognitive ability. At 24 months, BMI continued to improve (17.73 ± 3.54 kg/m2) while improvements in psychiatric symptoms and normal cognitive ability were maintained. Social functioning also improved by the 2-year follow-up. By the end of the study, 12 patients were weight restored, five patients had a 30% BMI increase which brought them to a low-normal range (16.0-18.5 kg/m2), 11 patients had low BMIs (15.0-16.0 kg/m2), and 17 patients had very low BMIs (<15.0 kg/m2). Additionally, 24 of the 28 patients were able to restore normal menses by the end of treatment.
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Diagnostic and Statistical Manual (DSM)
Psychology
Social Science
Health Sciences
Empirical Science
Science
Life Science / Biology
Natural Science
Clinical Practice of Psychology