Concept

Endothelial Dysfunction May Contribute to COVID-19 Morbidity and Mortality in Obese Patients

Endothelial dysfunction is associated with obesity and has been shown to lead to inflammation, oxidative stress, and vascular endothelial cell apoptosis. These conditions may contribute to cytokine storm syndrome which is known to exacerbate COVID-19. Additionally, the chronic inflammation and impaired ability to break down blood clots caused by endothelial dysfunction may lead to thrombosis, a condition that is thought to be mechanistically involved in severe lung damage and death in SARS-CoV-2 infections.

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Updated 2021-02-22

Tags

SARS-CoV-2 (COVID-19)

Biomedical Sciences

Disability Studies

Social Science

Empirical Science

Science