1Cademy - Method of Determining Role of ORF3a of SARS-CoV2 in apoptosis

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Mechanisms and Key Concepts to Understand Role of ORF3a in Apoptosis

Concept

Method of Determining Role of ORF3a of SARS-CoV2 in apoptosis

The presence of specific molecules that play a role in triggering apoptosis was analyzed based on the expression of ORF3a in transfected HEK293T cells.

Updated 2020-08-18

Contributors are:

Arvind Natarajan

🏆 3

Who are from:

Ohio State University, Columbus

🏆 3

References

The ORF3a protein of SARS-CoV-2 induces apoptosis in cells

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The Role of ORF3a protein in apoptosis of host cells: Caspase-8 and Bcl-2
The Role of ORF3a protein in apoptosis of host cells: Other Molecules of Mitochondrion-dependent Apoptosis
The Role of ORF3a protein in apoptosis of host cells: Caspase-3

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