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Concept
NR3C1 Gene
- Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1) encodes glucocorticoid receptor.
- Can function as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription.
- Can function as a regulator of other transcription factors.
- It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues.
- Mutations in this gene are associated with generalized glucocorticoid resistance.
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Updated 2021-10-03
Tags
Behavioral Neuroscience
Psychology
Neuroscience (Neurobiology)
Social Science
Empirical Science
Science
Life Science / Biology
Biomedical Sciences
Related
Chromosome
NR3C1 Gene
Gene therapy
Polygenic
Traits
Two identical twins, who share the exact same genetic makeup, were separated at birth and raised in significantly different environments. As adults, Twin A is outgoing and confident, while Twin B is shy and anxious. Based on the modern understanding of how genes influence traits, what is the most likely explanation for this difference in their psychological characteristics?
Analysis of Twin Outcomes
Alleles
Mutation