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Pressures on Ions During Resting Potential

During the resting state, two main forces act on ions across the neuronal membrane. The first is diffusion, where ions move down their concentration gradient. Specifically, sodium (Na+), being more concentrated outside the cell, is driven inward, while potassium (K+), being more concentrated inside, is driven outward. The second force is electrostatic pressure, arising from the net negative charge inside the cell. This electrical gradient provides an additional force attracting positively charged ions like sodium into the neuron.

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Updated 2026-04-26

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